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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK1IP1 All Species: 14.24
Human Site: S327 Identified Species: 24.1
UniProt: Q9NWT1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWT1 NP_060376.2 392 43964 S327 S P V S K E Q S K I G K K E P
Chimpanzee Pan troglodytes XP_518863 393 44017 S328 S P V S K E Q S K I G K K E P
Rhesus Macaque Macaca mulatta XP_001087458 392 43967 S327 S P V S K E Q S K I G K K E P
Dog Lupus familis XP_535884 391 43743 S329 S A V S K E Q S K I N K R E A
Cat Felis silvestris
Mouse Mus musculus Q9DCE5 382 42097 D322 P A A E P C P D Q P K T I E K
Rat Rattus norvegicus NP_001032433 382 42216 D322 P A T E P C P D Q P K T I E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514604 358 39493 V299 L P A A E A A V Q G N E E Q Q
Chicken Gallus gallus Q5ZKU8 369 41214 A310 M K E N C G K A A T S T E A N
Frog Xenopus laevis Q68FJ6 363 40513 S304 C L S A W L P S G V D H K E K
Zebra Danio Brachydanio rerio Q6TNS2 368 40882 P309 T C L C V W M P G E T K E T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181466 538 58474 G434 H N G G A A S G R I G N K E P
Poplar Tree Populus trichocarpa XP_002318775 332 35851 L273 T V D D P Y L L A S A S S D G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176683 345 37437 G286 I G S A S S D G I I R V W D V
Baker's Yeast Sacchar. cerevisiae P20484 468 53654 L405 E R L N C L T L C D E S I E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.1 85.4 N.A. 72.4 75.2 N.A. 65 63 60.4 53 N.A. N.A. N.A. N.A. 27.7
Protein Similarity: 100 99.7 97.6 92.8 N.A. 83.9 83.4 N.A. 76.5 78.5 75 69.6 N.A. N.A. N.A. N.A. 44.8
P-Site Identity: 100 100 100 73.3 N.A. 6.6 6.6 N.A. 6.6 0 20 6.6 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 80 N.A. 13.3 13.3 N.A. 46.6 26.6 33.3 26.6 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: 26.2 N.A. N.A. 27 20.9 N.A.
Protein Similarity: 46.1 N.A. N.A. 47.9 37.8 N.A.
P-Site Identity: 0 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 15 22 8 15 8 8 15 0 8 0 0 8 15 % A
% Cys: 8 8 0 8 15 15 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 0 8 15 0 8 8 0 0 15 0 % D
% Glu: 8 0 8 15 8 29 0 0 0 8 8 8 22 65 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 8 0 8 0 15 15 8 29 0 0 0 8 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 8 43 0 0 22 0 0 % I
% Lys: 0 8 0 0 29 0 8 0 29 0 15 36 36 0 29 % K
% Leu: 8 8 15 0 0 15 8 15 0 0 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 15 0 0 0 0 0 0 15 8 0 0 8 % N
% Pro: 15 29 0 0 22 0 22 8 0 15 0 0 0 0 29 % P
% Gln: 0 0 0 0 0 0 29 0 22 0 0 0 0 8 8 % Q
% Arg: 0 8 0 0 0 0 0 0 8 0 8 0 8 0 0 % R
% Ser: 29 0 15 29 8 8 8 36 0 8 8 15 8 0 0 % S
% Thr: 15 0 8 0 0 0 8 0 0 8 8 22 0 8 0 % T
% Val: 0 8 29 0 8 0 0 8 0 8 0 8 0 0 8 % V
% Trp: 0 0 0 0 8 8 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _